{"id":3239,"date":"2023-07-03T09:43:17","date_gmt":"2023-07-03T07:43:17","guid":{"rendered":"https:\/\/genosafe.com\/?page_id=3239"},"modified":"2026-04-13T16:23:37","modified_gmt":"2026-04-13T14:23:37","slug":"mediatheque","status":"publish","type":"page","link":"https:\/\/genosafe.com\/fr\/mediatheque\/","title":{"rendered":"M\u00e9diath\u00e8que"},"content":{"rendered":"<div id=\"cover\" class=\"cover wp-block-group eplus-wrapper has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-12dd3699 wp-block-group-is-layout-constrained eplus-styles-uid-3a4e68\">\n<div class=\"wp-block-group eplus-wrapper has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\"><div class=\"wp-block-columns eplus-wrapper is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex eplus-styles-uid-669d26\"><div class=\"wp-block-column eplus-wrapper is-layout-flow wp-block-column-is-layout-flow eplus-styles-uid-650f00\">\n<h2 class=\" wp-block-heading eplus-wrapper\">M\u00e9diath\u00e8que<\/h2>\n\n\n\n<p class=\" eplus-wrapper\">Retrouvez dans notre m\u00e9diath\u00e8que en ligne toutes les publications institutionnelles et scientifiques, acc\u00e9dez \u00e0 nos brochures, nos avanc\u00e9es et innovations en d\u00e9veloppement analytique, et restez inform\u00e9 de nos \u00e9v\u00e9nements, conf\u00e9rences et actualit\u00e9s.<\/p>\n<\/div>\n\n\n<div class=\"wp-block-column eplus-wrapper is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n<\/div><\/div>\n<\/div>\n\n\n<div id=\"evenements\" class=\"evenements wp-block-group eplus-wrapper has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group eplus-wrapper has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-12dd3699 wp-block-group-is-layout-constrained\">\n<h2 class=\" wp-block-heading has-text-align-left eplus-wrapper\"><strong>\u00c9v\u00e9nements<\/strong> \u00e0 venir<\/h2>\n<\/div>\n\n\n<div class=\"wp-block-columns eplus-wrapper is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex eplus-styles-uid-87168f\">\n<div class=\"wp-block-column eplus-wrapper is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped eplus-wrapper wp-block-gallery-1\">\n<figure class=\" wp-block-image size-full eplus-wrapper\"><img loading=\"lazy\" decoding=\"async\" width=\"850\" height=\"1000\" data-id=\"3727\" src=\"https:\/\/genosafe.com\/app\/uploads\/2026\/04\/Participation-congres-FR-5.png\" alt=\"\" class=\"wp-image-3727\" srcset=\"https:\/\/genosafe.com\/app\/uploads\/2026\/04\/Participation-congres-FR-5.png 850w, https:\/\/genosafe.com\/app\/uploads\/2026\/04\/Participation-congres-FR-5-255x300.png 255w, https:\/\/genosafe.com\/app\/uploads\/2026\/04\/Participation-congres-FR-5-768x904.png 768w\" sizes=\"auto, (max-width: 850px) 100vw, 850px\" \/><\/figure>\n<\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column eplus-wrapper is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped eplus-wrapper wp-block-gallery-2\">\n<figure class=\" wp-block-image size-full eplus-wrapper\"><img loading=\"lazy\" decoding=\"async\" width=\"850\" height=\"1000\" data-id=\"3725\" src=\"https:\/\/genosafe.com\/app\/uploads\/2026\/04\/Participation-congres-FR-6.png\" alt=\"\" class=\"wp-image-3725\" srcset=\"https:\/\/genosafe.com\/app\/uploads\/2026\/04\/Participation-congres-FR-6.png 850w, https:\/\/genosafe.com\/app\/uploads\/2026\/04\/Participation-congres-FR-6-255x300.png 255w, https:\/\/genosafe.com\/app\/uploads\/2026\/04\/Participation-congres-FR-6-768x904.png 768w\" sizes=\"auto, (max-width: 850px) 100vw, 850px\" \/><\/figure>\n<\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column eplus-wrapper is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped eplus-wrapper wp-block-gallery-3\">\n<figure class=\" wp-block-image size-full eplus-wrapper\"><img loading=\"lazy\" decoding=\"async\" width=\"850\" height=\"1000\" data-id=\"3723\" src=\"https:\/\/genosafe.com\/app\/uploads\/2026\/04\/Participation-congres-FR-7.png\" alt=\"\" class=\"wp-image-3723\" srcset=\"https:\/\/genosafe.com\/app\/uploads\/2026\/04\/Participation-congres-FR-7.png 850w, https:\/\/genosafe.com\/app\/uploads\/2026\/04\/Participation-congres-FR-7-255x300.png 255w, https:\/\/genosafe.com\/app\/uploads\/2026\/04\/Participation-congres-FR-7-768x904.png 768w\" sizes=\"auto, (max-width: 850px) 100vw, 850px\" \/><\/figure>\n<\/figure>\n<\/div>\n<\/div><\/div>\n\n\n\n<div id=\"actus\" class=\"actus wp-block-group eplus-wrapper has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group eplus-wrapper has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<h2 class=\" wp-block-heading eplus-wrapper\">Nos <strong>actus<\/strong><\/h2>\n\n\n<div class=\"juicer-feed\" data-feed-id=\"genosafe-c5bfd755-5d33-4729-9bb7-986a6922ecde\"><\/div>\n<\/div>\n<\/div>\n\n\n\n<div id=\"a-la-une\" class=\"a-la-une wp-block-group eplus-wrapper has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group eplus-wrapper has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-12dd3699 wp-block-group-is-layout-constrained\">\n<h2 class=\" wp-block-heading eplus-wrapper\"><strong>Ressources<\/strong> t\u00e9l\u00e9chargeables<\/h2>\n\n\n<div class=\"wp-block-columns eplus-wrapper is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex eplus-styles-uid-ae3050\">\n<div class=\"wp-block-column eplus-wrapper is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"push_bg small-push right-focus\" style=\"background-image: url('https:\/\/genosafe.com\/app\/uploads\/2023\/07\/cover-home.jpg');\">\n    <a href=\"https:\/\/genosafe.com\/app\/uploads\/2025\/04\/Brochure-Generale.pdf\" target=\"_blank\">\n        <div class=\"push_mask\" style=\"background-color: rgba(81, 181, 226, 0.7);\">\n            <div class=\"push_content style-download\">\n                <div class=\"push_title\">\n                    BROCHURE                <\/div>\n                <div class=\"push_link\">\n                    T\u00e9l\u00e9chargez notre nouvelle brochure                <\/div>\n            <\/div>\n        <\/div>\n    <\/a>\n<\/div>\n\n\n<div class=\"push_bg small-push center-focus\" style=\"background-image: url('');\">\n    <a href=\"https:\/\/genosafe.com\/app\/uploads\/2025\/06\/Preclinique-testing-pour-site-internet.pdf\" target=\"_blank\">\n        <div class=\"push_mask\" style=\"background-color: rgba(231, 116, 63, 1);\">\n            <div class=\"push_content style-download\">\n                <div class=\"push_title\">\n                    Tests pr\u00e9cliniques                <\/div>\n                <div class=\"push_link\">\n                    T\u00e9l\u00e9chargez notre brochure                <\/div>\n            <\/div>\n        <\/div>\n    <\/a>\n<\/div>\n\n\n<div class=\"push_bg small-push center-focus\" style=\"background-image: url('');\">\n    <a href=\"https:\/\/genosafe.com\/app\/uploads\/2025\/11\/Communique-de-presse-FR.pdf\" target=\"_blank\">\n        <div class=\"push_mask\" style=\"background-color: rgba(239, 202, 143, 1);\">\n            <div class=\"push_content style-download\">\n                <div class=\"push_title\">\n                    Communiqu\u00e9 de presse                <\/div>\n                <div class=\"push_link\">\n                    T\u00e9l\u00e9chargez notre communiqu\u00e9 de presse                <\/div>\n            <\/div>\n        <\/div>\n    <\/a>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-column eplus-wrapper is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"push_bg small-push center-focus\" style=\"background-image: url('');\">\n    <a href=\"https:\/\/genosafe.com\/app\/uploads\/2025\/04\/GenoSafe-presentation-2025-v2-1.pdf\" target=\"_blank\">\n        <div class=\"push_mask\" style=\"background-color: rgba(81, 181, 226, 1);\">\n            <div class=\"push_content style-download\">\n                <div class=\"push_title\">\n                    Pr\u00e9sentation Genosafe                <\/div>\n                <div class=\"push_link\">\n                    Consultez notre pr\u00e9sentation                <\/div>\n            <\/div>\n        <\/div>\n    <\/a>\n<\/div>\n\n\n<div class=\"push_bg small-push center-focus\" style=\"background-image: url('');\">\n    <a href=\"https:\/\/genosafe.com\/app\/uploads\/2025\/06\/brochure-QC-pour-site-internet.pdf\" target=\"_blank\">\n        <div class=\"push_mask\" style=\"background-color: rgba(231, 116, 63, 1);\">\n            <div class=\"push_content style-download\">\n                <div class=\"push_title\">\n                    Contr\u00f4le qualit\u00e9                 <\/div>\n                <div class=\"push_link\">\n                    T\u00e9l\u00e9chargez notre brochure                <\/div>\n            <\/div>\n        <\/div>\n    <\/a>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-column eplus-wrapper is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"push_bg small-push center-focus\" style=\"background-image: url('');\">\n    <a href=\"https:\/\/genosafe.com\/app\/uploads\/2025\/09\/Poster_ADA-1.pdf\" target=\"_blank\">\n        <div class=\"push_mask\" style=\"background-color: rgba(81, 181, 226, 1);\">\n            <div class=\"push_content style-download\">\n                <div class=\"push_title\">\n                    Strat\u00e9gie de l&rsquo;ADA pour les programmes AAV                <\/div>\n                <div class=\"push_link\">\n                    T\u00e9l\u00e9chargez notre poster                <\/div>\n            <\/div>\n        <\/div>\n    <\/a>\n<\/div>\n\n\n<div class=\"push_bg small-push center-focus\" style=\"background-image: url('');\">\n    <a href=\"https:\/\/genosafe.com\/app\/uploads\/2025\/06\/Clinical-bioanalyses-pour-site-internet.pdf\" target=\"_blank\">\n        <div class=\"push_mask\" style=\"background-color: rgba(231, 116, 63, 1);\">\n            <div class=\"push_content style-download\">\n                <div class=\"push_title\">\n                    Bioanalyse clinique                <\/div>\n                <div class=\"push_link\">\n                    T\u00e9l\u00e9chargez notre brochure                <\/div>\n            <\/div>\n        <\/div>\n    <\/a>\n<\/div><\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<div id=\"publications\" class=\"publications wp-block-group eplus-wrapper has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group eplus-wrapper has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<h2 class=\" wp-block-heading eplus-wrapper\"><strong>Publications<\/strong> scientifiques<\/h2>\n\n\n\n<p class=\" eplus-wrapper\"><strong>Polyfunctional T cells and unique cytokine clusters imprint the anti rAAV2\/rAAV9 vector immune response<\/strong>.  Stephan J Holtkamp, Florian R Lagoda, Adam Lister, Pradeep Harish, Ulrike Kleymann, Theresa Pesh, Chain Fen Soon, Munir Pirmohamed, Dean Naisbitt, Mark Trautwein. Front Immunol. 2024 Nov.<\/p>\n\n\n\n<div class=\"wp-block-buttons eplus-wrapper is-layout-flex wp-container-core-buttons-is-layout-168ce233 wp-block-buttons-is-layout-flex\"><div class=\" wp-block-button eplus-wrapper eplus-styles-uid-71bb68\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39654900\/\" target=\"_blank\" rel=\"noreferrer noopener\">Lire sur pubmed<\/a><\/div><\/div>\n\n\n\n<p class=\" eplus-wrapper\"><strong>Does gene therapies clinical research in rare diseases reflects the competitivity of the country: Example of France<\/strong>.  Lutsyk K, Gicquel T, Cortial L, Forget S, Braun S, Boyer PO, Laugel V, Blin O. Therapie. 2024 Sep-Oct.<\/p>\n\n\n\n<div class=\"wp-block-buttons eplus-wrapper is-layout-flex wp-container-core-buttons-is-layout-168ce233 wp-block-buttons-is-layout-flex\"><div class=\" wp-block-button eplus-wrapper eplus-styles-uid-76bdbb\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38458946\/\" target=\"_blank\" rel=\"noreferrer noopener\">Lire sur pubmed<\/a><\/div><\/div>\n\n\n\n<p class=\" eplus-wrapper\"><strong>Efficacy, pharmacokinetics, and safety in the mouse and primate retina of dual AAV vectors for Usher syndrome type 1B<\/strong>. Ferla R, Dell&rsquo;Aquila F, Doria M, Ferraiuolo M, Noto A, Grazioli F, Ammendola V, Testa F, Melillo P, Iodice C, Risca G, Tedesco N, le Brun PR, Surace EM, Simonelli F, Galimberti S, Valsecchi MG, Marteau JB, Veron P, Colloca S, Auricchio A. Mol Ther Methods Clin Dev. 2023 Feb.<\/p>\n\n\n\n<div class=\"wp-block-buttons eplus-wrapper is-layout-flex wp-block-buttons-is-layout-flex\"><div class=\" wp-block-button eplus-wrapper eplus-styles-uid-abd3e4\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36910588\/\" target=\"_blank\" rel=\"noreferrer noopener\">Lire sur pubmed<\/a><\/div><\/div>\n\n\n\n<p class=\" eplus-wrapper\"><strong>Liver-Directed Adeno-Associated Virus-Mediated Gene Therapy for Mucopolysaccharidosis Type VI<\/strong>. Brunetti-Pierri N, Ferla R, Ginocchio VM, Rossi A, Fecarotta S, Romano R, Parenti G, Yildiz Y, Zancan S, Pecorella V, Dell&rsquo;Anno M, Graziano M, Alliegro M, Andria G, Santamaria F, Brunetti-Pierri R, Simonelli F, Nigro V, Vargas M, Servillo G, Borgia F, Soscia E, Gargaro M, Funghini S, Tedesco N, Le Brun PR, Rupar CA, Prasad C, O&rsquo;Callaghan M, Mitchell JJ, Danos O, Marteau JB, Galimberti S, Valsecchi MG, Veron P, Mingozzi F, Fallarino F, la Marca G, Sivri HS, Auricchio A.NEJM Evid. 2022 Jul.<\/p>\n\n\n\n<div class=\"wp-block-buttons eplus-wrapper is-layout-flex wp-block-buttons-is-layout-flex\"><div class=\" wp-block-button eplus-wrapper eplus-styles-uid-afa1a6\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38319253\/\" target=\"_blank\" rel=\"noreferrer noopener\">Lire sur pubmed<\/a><\/div><\/div>\n\n\n\n<p class=\" eplus-wrapper\"><strong>Confirmatory detection of neutralizing antibodies to AAV gene therapy using a cell-based transduction inhibition assay<\/strong>. Kasprzyk T, Triffault S, Long BR, Zoog SJ, Vettermann C. Mol Ther Methods Clin Dev. 2022 Jan.<\/p>\n\n\n\n<div class=\"wp-block-buttons eplus-wrapper is-layout-flex wp-block-buttons-is-layout-flex\"><div class=\" wp-block-button eplus-wrapper eplus-styles-uid-f0e5dc\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35141351\/\" target=\"_blank\" rel=\"noreferrer noopener\">Lire sur pubmed<\/a><\/div><\/div>\n\n\n\n<p class=\" eplus-wrapper\"><strong>Preclinical Evaluation of a Cell-Based Gene Therapy Using the Sleeping Beauty Transposon System in Choroidal Neovascularization<\/strong>. Hernandez M, Recalde S, Garcia-Garcia L, Bezunartea J, Miskey C, Johnen S, Diarra S, Sebe A, Rodriguez-Madoz JR, Pouillot S, Marie C, Izsv\u00e1k Z, Scherman D, Kropp M, Prosper F, Thumann G, Ivics Z, Garcia-Layana A, Fernandez-Robredo P.Mol Ther Methods Clin Dev. 2019 Nov.<\/p>\n\n\n\n<div class=\"wp-block-buttons eplus-wrapper is-layout-flex wp-block-buttons-is-layout-flex\"><div class=\" wp-block-button eplus-wrapper eplus-styles-uid-e3b989\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31890733\/\" target=\"_blank\" rel=\"noreferrer noopener\">Lire sur pubmed<\/a><\/div><\/div>\n\n\n\n<p class=\" eplus-wrapper\"><strong>Strategy to detect pre-existing immunity to AAV gene therapy.<\/strong> Falese L, Sandza K, Yates B, Triffault S, Gangar S, Long B, Tsuruda L, Carter B, Vettermann C, Zoog SJ, Fong S. Gene Ther. 2017 Dec.<\/p>\n\n\n\n<div class=\"wp-block-buttons eplus-wrapper is-layout-flex wp-block-buttons-is-layout-flex\"><div class=\" wp-block-button eplus-wrapper eplus-styles-uid-2505bc\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29106404\/\" target=\"_blank\" rel=\"noreferrer noopener\">Lire sur pubmed<\/a><\/div><\/div>\n\n\n\n<p class=\" eplus-wrapper\"><strong>Non-clinical Safety and Efficacy of an AAV2\/8 Vector Administered Intravenously for Treatment of Mucopolysaccharidosis Type VI.<\/strong> Ferla R, Alliegro M, Marteau JB, Dell&rsquo;Anno M, Nusco E, Pouillot S, Galimberti S, Valsecchi MG, Zuliani V, Auricchio A. Mol Ther Methods Clin Dev. 2017 Jul.<\/p>\n\n\n\n<div class=\"wp-block-buttons eplus-wrapper is-layout-flex wp-block-buttons-is-layout-flex\"><div class=\" wp-block-button eplus-wrapper eplus-styles-uid-dd767b\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28932756\/\" target=\"_blank\" rel=\"noreferrer noopener\">Lire sur pubmed<\/a><\/div><\/div>\n\n\n\n<p class=\" eplus-wrapper\"><strong>\u00ab\u00a0RCL-Pooling Assay\u00a0\u00bb: A Simplified Method for the Detection of Replication-Competent Lentiviruses in Vector Batches Using Sequential Pooling.<\/strong> Corre G, Dessainte M, Marteau JB, Dalle B, Fenard D, Galy A. Hum Gene Ther. 2016 Feb.<\/p>\n\n\n\n<div class=\"wp-block-buttons eplus-wrapper is-layout-flex wp-block-buttons-is-layout-flex\"><div class=\" wp-block-button eplus-wrapper eplus-styles-uid-e94ab4\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26886834\/\" target=\"_blank\" rel=\"noreferrer noopener\">Lires sur pubmed<\/a><\/div><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>M\u00e9diath\u00e8que Retrouvez dans notre m\u00e9diath\u00e8que en ligne toutes les publications institutionnelles et scientifiques, acc\u00e9dez \u00e0 nos brochures, nos avanc\u00e9es et innovations en d\u00e9veloppement analytique, et restez inform\u00e9 de nos \u00e9v\u00e9nements, conf\u00e9rences et actualit\u00e9s. \u00c9v\u00e9nements \u00e0 venir Nos actus Ressources t\u00e9l\u00e9chargeables Publications scientifiques Polyfunctional T cells and unique cytokine clusters imprint the anti rAAV2\/rAAV9 vector immune [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":6,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"editor_plus_copied_stylings":"{}","footnotes":""},"class_list":["post-3239","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>GenoSafe | M\u00e9diath\u00e8que \u2013 Publications &amp; Actualit\u00e9s<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/genosafe.com\/fr\/mediatheque\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"GenoSafe | M\u00e9diath\u00e8que \u2013 Publications &amp; Actualit\u00e9s\" \/>\n<meta property=\"og:description\" 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